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BacPath9 Program

The Molecular Biology of Bacterial Pathogens

Mantra Erskine Beach Resort
Lorne, Victoria
23-26 September 2007

Scientific Program:

 Sunday 23 September

 (Internet access sponsored by Pacific Laboratory Products)

 4.00 pm 

Registration (Abstract book sponsored by Pfizer Animal Health)
(Lanyard provided by Bio-Rad)

 4.30 pm 

Afternoon tea (Sponsored by American Society for Microbiology)

 6.00 pm

Welcome and opening: Julian Rood

 Opening Session                                                                                  Chair: Tim Stinear

 (Sponsored by ARC Centre of Excellence in Structural and Functional Microbial Genomics)

 6.15 pm

Carmen Buchrieser (Institut Pasteur)
Legionella pneumophila and Legionella longbeachae pathogenesis: new insights gained from comparative and functional genomics

 7.15 pm

Dinner

 Session: Genomics                                                                               Chair: Neville Firth

 (Sponsored by Roche)

 8.30 pm

Scott Beatson (University of Queensland)
The genome sequence of an asymptomatic bacteriuria Escherichia coli: from guts to glory

 8.50 pm

Roland Brosch (Institut Pasteur)
Molecular determinants of pathogenicity and attenuation -insights from genome analyses of BCG and Mycobacterium tuberculosis

 9.10 pm

Tim Stinear (Monash University)
The complete genome sequence of Mycobacterium marinum

 9.30 pm

Welcome Mixer (Sponsored by Lomb)

 Monday September 24

 (Internet access sponsored by Pacific Laboratory Products)

 Session: Clostridium difficile: an emerging pathogen                      Chair: Julian Rood

 (Sponsored by ARC Centre of Excellence in Structural and Functional Microbial Genomics)

 8.30 am

Klaus Aktories (University of Freiburg)
New insights into structure and functions of Clostridium difficile toxins

 9.30 am

Dena Lyras (Monash University)
Genetic and Functional Analysis of the Major Toxin Genes of Clostridium difficile

 9.50 am

Glen Carter (Monash University)
The CdtR response regulator activates the production of binary toxin in Clostridium difficile

 10.10 am

Morning tea (Sponsored by Eppendorf)

 Session: Biofilms                                                                             Chair: Mark Schembri

 (Sponsored by Department of Microbiology & Immunology, University of Melbourne)

 10.40 am

Deborah Baldi (University of Melbourne)
Type II protein secretion and biofilm formation in Enteropathogenic E. coli

 11.00 am

Cheryl-lynn Ong (University of Queensland)
Type 3 fimbriae promote biofilm formation by uropathogenic Escherichia coli

 11.20 am

Stuart Dashper (University of Melbourne)
The effect of biofilm culture on the cell envelope proteome of
Porphyromonas gingivalis W50

 11.40 am

Alvin Lo (University of Melbourne)
Transcriptomic analysis of Porphyromonas gingivalis in biofilm versus planktonic culture

 12.00 pm

Cynthia Whitchurch (Monash University)
Extracellular DNA is required for biofilm development and colony expansion in Pseudomonas aeruginosa

 12.20 pm

Lynne Turnbull (Monash University)
Pseudomonas aeruginosa
biofilms are competent for natural transformation

 12.40 pm

Lunch

 2.00 pm

Networking

 4.00 pm

Afternoon tea (Sponsored by Scientifix)

 Session: Virulence Factors 1                                                               Chair:  Dena Lyras

 (Sponsored by Department of Microbiology & Immunology, University of Melbourne)

 4.30 pm

Stephen Kidd (University of Queensland)
A role in pathogenesis for NmlR; a transcription factor from the MerR family

 4.50 pm

Emily Hart (University of Melbourne)
Identification of a novel putative transcriptional regulator that is an essential virulence determinant of Citrobacter rodentium

 5.10 pm

Wilhelmina Huston (Queensland University of Technology)
HtrA from Chlamydia trachomatis is a temperature activated serine protease with an unusual preference for proline at site of cleavage

 5.30 pm

Corrine Porter (Monash University)
A Disulphide Tethered Loop Confers Elastase-like Activity on AprV2, an Acidic Protease Secreted by Dichelobacter nodosus

 5.50 pm

Anthony Keyburn (CSIRO)
NetB, a novel Clostridium perfringens toxin that is an essential virulence factor for necrotic enteritis in chickens

 6.10 pm

Emma Byres (Monash University)
The structure of subunit B of Escherichia coli subtilase cytotoxin, AB5, reveals determinants of toxin receptor-binding specificity

 6.30 pm

Dinner

 8.00 pm

Poster Session 1 (Sponsored by CRC for Oral Health Science)

 Tuesday 25 September

 (Internet access sponsored by Pacific Laboratory Products)

 Session: Gene Regulation in Pseudomonas                         Chair: Cynthia Whitchurch

 (Sponsored by Micromon)

 8.30 am

Stephen Lory (Harvard University)
Regulatory networks control the expression of Pseudomonas aeruginosa virulence determinants at transcriptional and post-transcriptional levels

 9.30 am

Iain Lamont (University of Otago)
Interactions between iron signaling pathways in the bacterium Pseudomonas aeruginosa

 9.50 am

Sanjay Swarup (National University of Singapore)
Regulatory effect of c-di-GMP signalling on metabolic and other pathways in Pseudomonas aeruginosa

 10.10 am

Morning tea (Sponsored by Olympus and Crown Scientific)

 Session: Virulence Factors 2                                                              Chair: Debbie Baldi

 (Sponsored by Australian Society for Microbiology)

 10.40 am

John Boyce (Monash University)
Decoration of P. multocida LPS by phosphocholine is important for virulence

 11.00 am

Abigail Clements (University of Melbourne)
Investigating the role of cell surface saccharides in the virulence ofKlebsiella pneumoniae

 11.20 am

Christine Gillen (University of Wollongong)
Apolipoprotein AI binding, fibronectin binding and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete

 11.40 am

Catherine Kennedy (Monash University)
Clostridium septicum a-toxin mutations have different effects in vitro and in vivo and greater activity against nucleated cells

 12.00 pm

Hayley Newton (Monash University)
The
Sel1 repeat protein LpnE is a secreted virulence determinant of Legionella pneumophila

 12.20 pm

Fiona Sansom (Monash University)
Ecto-nucleoside triphosphate diphosphohydrolases of Legionella pneumophila

 12.40 pm

Lunch

 2.00 pm

Networking

 4.00 pm

Afternoon tea (Sponsored by DKHS Australia)

 Session: Host-pathogen interactions                                           Chair: Richard Ferrero

 (Sponsored by Monash Infection and Immunity Network)

 4.30 pm

Grant Jenkin (Monash University)
The Effects of Mycolactone on Toll-Like Receptor Signalling

 4.50 pm

Alexandra Grubman (Monash University)
The innate immune molecule, Nod1, regulates direct killing of Helicobacter pylori by antimicrobial peptides

 5.10 pm

Jason Cole (University of Wollongong)
Dnase-mediated resistance to neutrophil killing provides selection pressure for a genetic and phenotypic switch promoting invasive group A streptococcal infection

 5.30 pm

David Hoke (Monash University)
LipL32 is an extracellular matrix-interacting protein of Leptospira interrogans

 5.50 pm

Michelle Dunstone (Monash University)
Unifying vertebrate defence and bacterial attack

 6.10 pm

Glen Ulett (University of Queensland)
Phylogenetic Lineage and Surface Protein 1 Affect the Opsonin-Independent Phagocytosis, Intracellular Survival, and Virulence of Group B Streptococcus

 6.30 pm

Dinner

 8.00 pm

Poster Session 2 (Sponsored by CRC for Oral Health Science)

 Wednesday 26 September

 (Internet access sponsored by Geneworks)

 Session: Molecular Bacteriology                                                    Chair: Melissa Brown

 (Sponsored by Micromon)

 8.30 am

Jennifer Parsons (Monash University)
Identification and characterization of TcpA, an FtsK/SpoIIIE homologue that is essential for transfer of the conjugative plasmid pCW3 in C. perfringens

 8.50 am

Meredith Hughes (Monash University)
Epsilon Toxin Plasmids of Clostridium perfringens Type D are Conjugative

 9.10 am

Stephen Kwong (University of Sydney)
Staphylococcus aureus
host-factors involved in replisome assembly at the replication origin of multiresistance plasmid pSK41

 9.30 am

Rebecca Towers (Charles Darwin University)
Architecture of the Fibronectin-Collagen-T antigen (FCT) region in group C and G Streptococcus dysgalactiae ssp equisimilis and comparison with group A Streptococcus pyogenes

 9.50 am

Karl Hassan (University of Sydney)
Flexibility of electrostatic interactions in the bivalent drug binding pocket of the Staphylococcus aureus multidrug transporter QacA

 10.10 am

Torsten Theis (University of Technology, Sydney)
Divide and Forfeit: Cell Division as an Antibacterial Target

 10.30 am

Morning tea (Sponsored by Applied Biosystems)

 Closing Session                                                                                   Chair: John Davies

 (Sponsored by Australian Society for Microbiology)

 11.00 am

Ben Adler (Monash University)
The surface of Pasteurella multocida: genetics, structure and pathogenesis

 12.00 pm

Summation and Close: Julian Rood and Cynthia Whitchurch
(Poster prizes provided by Olympus and Crown Scientific)

 12.30 pm

Lunch

 2.00 pm

Depart